Thalidomide and its dermatologic uses.
نویسندگان
چکیده
Thalidomide is a beneficial agent for treating a variety of refractory dermatologic disorders including erythema nodosom leprosum, lupus erythematosus, prurigo nodularis, actinic prurigo, pyoderma gangrenosum and aphthous stomatitis. Two thalidomide analogues, lenalidomide and CC-4047, are considerably more potent with decreased side effects when compared to thalidomide. They are currently undergoing trials and show promise, as they have increased immunomodulatory and anti-angiogenic activity. This category of medication and its use will be reviewed.
منابع مشابه
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ورودعنوان ژورنال:
- Acta dermatovenerologica Croatica : ADC
دوره 15 1 شماره
صفحات -
تاریخ انتشار 2007